The NoStra project aims at developing new strategies to improve the assessment of human exposure to fast elimination contaminants, such as non-persistent pesticides, bisphenols, phthalates, and other plastic-associated contaminants.

Urine & hair samples

In order to facilitate the implementation within epidemiological studies based on human cohorts, the approaches are based on non-invasive biological matrices such as urine and hair. The results obtained in this project will help to better design the approaches used for exposure assessment in order to improve the understanding of the adverse effects on health associated with exposure to non-persistent contaminants. 

Relevant publications

Biomonitoring of fast-elimination endocrine disruptors - Results from a 6-month follow-up on human volunteers with repeated urine and hair collection
July 15, 2021
2021 Jul. Sci Total Environ.778:146330. Epub 2021 Mar 9.
By: Fays F  Hardy EM   Palazzi P   Haan S  Beausoleil C   Appenzeller BMR.

Is there an optimal sampling time and number of samples for assessing exposure to fast elimination endocrine disruptors with urinary biomarkers?
December 10, 2020
2020 Dec. Sci Total Environ.747:141185. Epub 2020 Jul 25.
By: Fays F  Palazzi P  Hardy EM  Schaeffer C  Phillipat C  Zeimet E  Vaillant M  Beausoleil C  Rousselle C  Slama R  Appenzeller BMR.




• Inserm


Financial support



For more info

• Brice APPENZELLER - HBRU Group Leader